Department of Transportation

Drug & Alcohol Testing Resources

The Drug and Alcohol Testing Response Handbook is designed to give Drug and Alcohol Program Managers (DAPM) and Designated Employer Representatives (DER) a quick reference guide to assist in the day-to-day administration of a compliant FTA drug and alcohol testing program. The information contained in this Handbook is a summary of the information contained in 49 CFR Part 40, as amended, and Part 655 and is intended to be a supplement to FTA publications and the technical assistance tools provided on the FTA website (

To view the Drug and Alcohol Testing Response Handbook, please click on the link.​​​